bustling spontaneous mutation arose in Cdh23 gene. Homozygous mutant mice exhibit behavioral abnormalities such as hyperactivity, circling, head tossing and head tilting with vestibulocochlear defects. Viable and fertile, but it is difficult for homozygous female to nurse pups.
BUS/Idr-bus
BUS/Idr-bus
Neurobiology Research
愛知県心身障害者コロニー発達障害研究所・米澤 敏先生。KYF/MsIdr-Jsr系統に生じた自然突然変異。
BUS/Idr-bus
BUS/Idr-bus
Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li></ol>
false
C(3〜6か月)
愛知県心身障害者コロニー発達障害研究所
Developed by Satoshi Yonezawa, Institute for Developmental Research, Japan. Spontaneous mutation originally arosed in KYF/MsIdr-Jsr strain.
Inst. Dev. Res.
米澤 敏
Heterozygote (female) x Homozygote (male) [or Crossing to BUS/Idr-+/+(RBRC00072)]
Heterozygote (female) x Homozygote (male) [or Crossing to BUS/Idr-+/+(RBRC00072)]
C (3-6 months)
条件を付加しない。
Sensorineural Research
Satoshi YONEZAWA
RBRC00073
Cdh23遺伝子に生じたbus突然変異。ホモマウスは内耳有毛神経細胞変性を起こす。旋回、頭振の行動異常、内耳性難聴を呈する。ホモ雌は繁殖が可能なものの、育仔は困難。bus系統 (RBRC00073) 、コントロール (正常) 系統 (RBRC00072) 。
No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)